Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739403 | 1.00 | GPR119 (0.41) | GPR119GRIN1GRIN2BGPR6RAB9A | |
| SCHEMBL24739018 | 0.91 | GPR119 (0.37) | GPR119GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL24739441 | 0.87 | HRH3 (0.38) | GPR119HRH3 | |
| SCHEMBL24739423 | 0.86 | GPR119 (0.45) | GPR119GRIN1GRIN2BGPR6RBP4 | |
| SCHEMBL24739223 | 0.86 | GPR119 (0.45) | GPR119GRIN1GRIN2BGPR6RBP4 | |
| SCHEMBL24739542 | 0.85 | HRH3 (0.38) | GPR119GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL24739054 | 0.85 | GPR119 (0.42) | GPR119GRIN1GRIN2BALDH1A1MEN1 | |
| SCHEMBL24739388 | 0.81 | USP30 (0.43) | GPR119MEN1KMT2ATDP1 | |
| SCHEMBL24739557 | 0.81 | GPR119 (0.36) | GPR119GRIN1GRIN2BPDE4B | |
| SCHEMBL24739228 | 0.80 | P2RX3 (0.43) | GPR119ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |