Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863158 | 0.88 | GRIN1 (0.43) | HRH3KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24739536 | 0.87 | SLC6A4 (0.42) | HRH3KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24739445 | 0.87 | HRH3 (0.43) | HRH3KCNH2USP30 | |
| SCHEMBL12442601 | 0.87 | USP30 (0.49) | USP30 | |
| SCHEMBL7722106 | 0.86 | MCL1 (0.45) | FAAHUSP30 | |
| SCHEMBL24739420 | 0.85 | HRH3 (0.47) | HRH3KCNH2GHSRMGLLABHD6 | |
| SCHEMBL24739423 | 0.83 | GPR119 (0.45) | — | |
| SCHEMBL24739223 | 0.83 | GPR119 (0.45) | — | |
| SCHEMBL24739408 | 0.82 | HRH3 (0.54) | HRH3KCNH2GHSRMGLLABHD6 | |
| SCHEMBL24739025 | 0.81 | GRIN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |