Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739131 | 0.88 | P2RX3 (0.47) | GPR119MCL1USP30 | |
| SCHEMBL12442601 | 0.88 | USP30 (0.49) | GPR119MCL1USP30 | |
| SCHEMBL24739401 | 0.87 | HRH3 (0.47) | HRH3KCNH2USP30 | |
| SCHEMBL24739441 | 0.85 | HRH3 (0.38) | HRH3GPR119KCNH2MCL1EPHX2 | |
| SCHEMBL24739223 | 0.84 | GPR119 (0.45) | GPR119GRIN1GRIN2B | |
| SCHEMBL24739423 | 0.84 | GPR119 (0.45) | GPR119GRIN1GRIN2B | |
| SCHEMBL31051486 | 0.84 | HRH3 (0.42) | HRH3GPR119KCNH2MCL1GRIN1 | |
| SCHEMBL24739025 | 0.84 | GRIN1 (0.41) | GPR119GRIN1GRIN2B | |
| SCHEMBL24739551 | 0.84 | GRIN1 (0.41) | GPR119GRIN1GRIN2B | |
| SCHEMBL18618195 | 0.84 | TACR1 (0.41) | HRH3KCNH2MCL1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |