SCHEMBL24739619

SCHEMBL24739619

C=C(C)C(=O)NCCc1ccc(Oc2cc3c4c(cc(Oc5ccc(CCNC(=O)C(=C)C)cc5)c5c6c(Oc7ccc(CCNC(=O)C(=C)C)cc7)cc7c8c(cc(Oc9ccc(CCNC(=O)C(=C)C)cc9)c(c2c45)c86)C(=O)N(C(Cc2ccccc2)C(=O)N(C)c2ccccc2)C7=O)C(=O)N(C(Cc2ccccc2)C(=O)N(C)c2ccccc2)C3=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
POLB P06746 2/20 0.41
PLAAT3 P53816 4/20 0.37
PLAAT5 Q96KN8 4/20 0.37
PLAAT2 Q9NWW9 4/20 0.37
PLAAT4 Q9UL19 4/20 0.37
GAA P10253 2/20 0.36
ALDH1A1 P00352 1/20 0.36
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CAPN1 P07384 2/20 0.34
AADAT Q8N5Z0 1/20 0.34
THRB P10828 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24739615 0.90 POLB (0.41) KMT2APOLBPLAAT3PLAAT5PLAAT2
SCHEMBL24739825 0.88 POLB (0.40) KMT2APOLBPLAAT3PLAAT5PLAAT2
SCHEMBL24740741 0.88 POLB (0.41) KMT2APOLBGAAALDH1A1MEN1
SCHEMBL24740193 0.85 POLB (0.37) KMT2APOLBPLAAT3PLAAT5PLAAT2
SCHEMBL24740194 0.82 POLB (0.37) KMT2APOLBPLAAT3PLAAT5PLAAT2
SCHEMBL24704828 0.82 POLB (0.40) KMT2APOLBGAAALDH1A1MEN1
SCHEMBL24705130 0.82 KMT2A (0.43) KMT2APOLBGAAALDH1A1MEN1
SCHEMBL24705215 0.80 HSD11B1 (0.47) KMT2APOLBGAAALDH1A1MEN1
SCHEMBL24739702 0.79 POLB (0.39) KMT2APOLBGAAALDH1A1MEN1
SCHEMBL24739593 0.78 PLAAT3 (0.40) POLBPLAAT3PLAAT5PLAAT2PLAAT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220390841-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed