Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MYOC | Q99972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470643 | 0.81 | SCN4A (0.47) | SCN4ARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL1894479 | 0.77 | HTT (0.52) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1891269 | 0.76 | RAB9A (0.50) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2473217 | 0.75 | MAPT (0.43) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31564998 | 0.74 | MAPT (0.54) | SCN4ARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL2479691 | 0.73 | KDR (0.49) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2762677 | 0.71 | HTT (0.47) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30561407 | 0.71 | CYP1A2 (0.43) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13332032 | 0.71 | MEN1 (0.49) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15542346 | 0.70 | KDR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370429-A1 | P38 MAP KINASE INHIBITORS | Respivert Limited (GB) | 2011-10-05 | — | — | EP | disclosed |