Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MYOC | Q99972 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014374 | 0.88 | MEN1 (0.51) | KDM4EKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL2891270 | 0.86 | MAPT (0.41) | SCN4AKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL2475625 | 0.83 | ALDH1A1 (0.39) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2473665 | 0.83 | ALDH1A1 (0.48) | KDM4EKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL2473090 | 0.83 | RAF1 (0.45) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL3912768 | 0.82 | PARP10 (0.46) | KMT2AMEN1ALDH1A1NPC1MAPT | |
| SCHEMBL2892781 | 0.81 | NR4A1 (0.49) | — | |
| SCHEMBL2475270 | 0.81 | ALDH1A1 (0.42) | KDM4EKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL2474007 | 0.81 | SCN4A (0.44) | SCN4AKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL30561407 | 0.81 | CYP1A2 (0.43) | KMT2AMEN1ALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370429-A1 | P38 MAP KINASE INHIBITORS | Respivert Limited (GB) | 2011-10-05 | — | — | EP | disclosed |