Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021041 | 0.98 | USP2 (0.54) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL28992177 | 0.98 | USP2 (0.54) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL16059433 | 0.97 | USP2 (0.56) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL16060975 | 0.97 | USP2 (0.56) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL5827221 | 0.93 | CYP1A2 (0.48) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL7683870 | 0.93 | CYP1A2 (0.48) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| Methylamine SCHEMBL27773382 | 0.91 | CYP1A2 (0.52) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL15369772 | 0.91 | CYP1A2 (0.50) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL4449957 | 0.91 | ALDH1A1 (0.60) | TDP1USP2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL16670930 | 0.91 | ALDH1A1 (0.60) | TDP1USP2ALDH1A1ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |