Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848082 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL16670930 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL11850612 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL16059433 | 0.91 | USP2 (0.56) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL16060975 | 0.91 | USP2 (0.56) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL28992177 | 0.89 | USP2 (0.54) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL11021041 | 0.89 | USP2 (0.54) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL7424483 | 0.89 | ALDH1A1 (0.54) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| Hydrochloric Acid SCHEMBL9260562 | 0.89 | CYP1A2 (0.56) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL7293121 | 0.89 | ALDH1A1 (0.54) | ALDH1A1ALOX15TDP1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931327-B1 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-8541362-B2 | Cyclopropyl compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20090220451-A1 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1931327-A2 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007022532-A2 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220451-A1 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | PAICS, ABCB4, ABCB11 | ALDH1A1 2599/4885ALOX15 956/4885TDP1 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.