Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24743067 | 0.82 | CKS1B (0.42) | SIGMAR1TMEM97TDP1STK17BSTK17A | |
| SCHEMBL12874037 | 0.73 | CACNA1H (0.45) | CACNA1BCACNA1CCACNA1HTDP1STK17B | |
| SCHEMBL1186965 | 0.73 | CACNA1H (0.45) | CACNA1BCACNA1CCACNA1HTDP1STK17B | |
| SCHEMBL31687500 | 0.73 | SIGMAR1 (0.58) | SIGMAR1TMEM97TDP1MEN1KMT2A | |
| SCHEMBL13377000 | 0.72 | TDP1 (0.66) | TDP1STK17BSTK17ACKS1BSKP1 | |
| SCHEMBL25963691 | 0.71 | TDP1 (0.64) | TDP1STK17BSTK17ACKS1BSKP1 | |
| SCHEMBL31687499 | 0.71 | SIGMAR1 (0.58) | SIGMAR1TMEM97TDP1MEN1GAA | |
| SCHEMBL4600182 | 0.70 | SIGMAR1 (0.62) | SIGMAR1TMEM97 | |
| SCHEMBL31239022 | 0.70 | CACNA1B (0.42) | CACNA1BCACNA1CCACNA1HCACNA1GGAA | |
| SCHEMBL31687519 | 0.70 | ACKR3 (0.57) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206888-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-10-06 | — | — | WO | disclosed |