Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 11/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.58 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459336 | 0.92 | SIGMAR1 (0.55) | SIGMAR1TMEM97APP | |
| SCHEMBL30380101 | 0.88 | SIGMAR1 (0.61) | SIGMAR1TMEM97 | |
| SCHEMBL31687500 | 0.87 | SIGMAR1 (0.58) | SIGMAR1TMEM97APPACKR3 | |
| SCHEMBL31687499 | 0.87 | SIGMAR1 (0.58) | SIGMAR1TMEM97APPACKR3 | |
| SCHEMBL3151917 | 0.87 | SIGMAR1 (0.48) | SIGMAR1TMEM97APPACKR3OPRM1 | |
| SCHEMBL31687472 | 0.86 | SIGMAR1 (0.61) | SIGMAR1TMEM97ACKR3OPRM1OPRK1 | |
| SCHEMBL26000432 | 0.86 | AKT1 (0.53) | SIGMAR1TMEM97 | |
| SCHEMBL31687519 | 0.86 | ACKR3 (0.57) | SIGMAR1TMEM97APPACKR3 | |
| SCHEMBL24510674 | 0.85 | ACHE (0.59) | — | |
| SCHEMBL30958274 | 0.85 | ACHE (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620949-A1 | ACKR3 MODULATORS FOR CARDIOVASCULAR OR ANTIPLATELET THERAPY | Eberhard Karls Universität Tübingen (Medizinische Fakultät) (DE) | 2025-09-24 | — | — | EP | disclosed |
| EP-1914235-A1 | CHIRAL TETRA-HYDRO BETA-CARBOLINE DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | Universite de Lille 2 Droit et Santé (FR) | 2008-04-23 | — | — | EP | disclosed |
| EP-1914235-A1 | CHIRAL TETRA-HYDRO BETA-CARBOLINE DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | Universite de Lille 2 Droit et Santé (FR) | 2008-04-23 | — | — | EP | disclosed |
| WO-2008044144-A2 | CHIRAL TETRA-HYDRO BETA-CARBOLIC DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | UNIVERSITE DE LILLE 2, UNIVERSITÉ DU DROIT ET DE LA SANTÉ (FR) | 2008-04-17 | — | — | WO | disclosed |