Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187746 | 0.85 | HSD17B10 (0.43) | KIF11TDP1CYP1A2CYP1B1CYP2A6 | |
| SCHEMBL1286989 | 0.81 | CA4 (0.59) | RAB9ANPC1KIF11KCNH2CA4 | |
| SCHEMBL8648265 | 0.81 | CA4 (0.59) | RAB9ANPC1KIF11KCNH2CA4 | |
| SCHEMBL8858901 | 0.81 | CA4 (0.59) | RAB9ANPC1KIF11KCNH2CA4 | |
| SCHEMBL14856630 | 0.81 | CA4 (0.59) | RAB9ANPC1KIF11KCNH2CA4 | |
| SCHEMBL5051055 | 0.81 | CA4 (0.59) | RAB9ANPC1KIF11KCNH2CA4 | |
| SCHEMBL4191295 | 0.78 | RAB9A (0.45) | RAB9ANPC1KMT2AL3MBTL1TDP1 | |
| SCHEMBL19149263 | 0.78 | KMT2A (0.47) | RAB9ANPC1KMT2AL3MBTL1TDP1 | |
| SCHEMBL17295935 | 0.78 | KMT2A (0.47) | RAB9ANPC1KMT2AL3MBTL1TDP1 | |
| SCHEMBL16549994 | 0.75 | KMT2A (0.44) | RAB9ANPC1KMT2AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145435-A2 | LIPID COMPOSITIONS AND METHODS FOR DELIVERY TO IMMUNE CELLS | Life Technologies Corporation (US) | 2024-07-04 | — | — | WO | disclosed |
| WO-2023067132-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2023-04-27 | — | — | WO | disclosed |
| EP-3865135-A2 | NEUROACTIVE STEROIDS FOR USE IN THERAPY | Sage Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| US-10406237-B2 | Amine-containing transfection reagents and methods for making and using same | LIFE TECHNOLOLGIES CORPORATION (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3470395-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2640700-B1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | LIFE TECHNOLOGIES CORP (US) | 2018-10-31 | — | — | EP | disclosed |
| US-20180200374-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2018-07-19 | — | — | US | disclosed |
| US-9901642-B2 | Amine-containing transfection reagents and methods for making and using same | Life Technologies Corporation (US) | 2018-02-27 | — | — | US | disclosed |
| EP-3183262-A1 | NOVEL GLYCAN CONJUGATES AND USE THEREOF | Academia Sinica (TW) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016029071-A1 | NOVEL GLYCAN CONJUGATES AND USE THEREOF | ACADEMIA SINICA (TW) | 2016-02-25 | — | — | WO | disclosed |
| EP-2370436-A1 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | Link Medicine Corporation (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-2244694-A2 | THERAPEUTIC COMPOSITIONS COMPRISING AN AMINE-CONTAINING LIPID AND A PROTEIN | Shire Human Genetic Therapies, Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010057006-A9 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010057006-A1 | AZAQUINOLINONE DERIVATIVES AND USES THEREOF | LINK MEDICINE CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2009097332-A2 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
| EP-1912679-A4 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008144514-A2 | POLYOL-BASED POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-11-27 | — | — | WO | disclosed |
| EP-1912679-A2 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1849760-A1 | Ether compounds, compositions, and uses thereof | Esperion Therapeutics Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006138380-A2 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10406237-B2 | Amine-containing transfection reagents and methods for making and using same | SNRPA, NUDT21, SOAT2 | RAB9A 3132/4885NPC1 87/4885KMT2A 908/4885 |
| US-20180200374-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | SNRPA, NUDT21, SOAT2 | RAB9A 3132/4885NPC1 87/4885KMT2A 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.