SCHEMBL24744175

SCHEMBL24744175

CC1(C)c2ccccc2-c2c(O)ccc3cccc1c23

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.41
TYMS P04818 3/20 0.41
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 2/20 0.36
ATM Q13315 2/20 0.36
HSD17B10 Q99714 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
MAOA P21397 1/20 0.36
DHFR P00374 4/20 0.35
CDK2 P24941 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
HPGD P15428 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
PABPC1 P11940 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24744980 0.83 DHFR (0.40) PDK2TYMSALDH1A1TSHRHSD17B10
SCHEMBL9936344 0.80 PDK2 (0.56) PDK2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL29518254 0.78 ALDH1A1 (0.50) TYMSALDH1A1TSHRMAPK1ATM
SCHEMBL17263918 0.78 ALDH1A1 (0.50) TYMSALDH1A1TSHRMAPK1ATM
SCHEMBL592159 0.76 ALDH1A1 (0.42) TYMSALDH1A1TSHRMAPK1ATM
SCHEMBL31395712 0.75 ALDH1A1 (0.50) TYMSALDH1A1TSHRMAPK1ATM
SCHEMBL24744577 0.75 TYMS (0.37) PDK2TYMSALDH1A1TSHRMAPK1
SCHEMBL11811052 0.75 PDK2 (0.42) PDK2ALDH1A1MAPK1ATMHSD17B10
SCHEMBL5894727 0.74 HSD17B10 (0.56) PDK2ALDH1A1TSHRMAPK1ATM
SCHEMBL13372146 0.74 PDK2 (0.45) PDK2ALDH1A1TSHRMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022260240-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-15 WO disclosed