Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30115707 | 0.83 | SRD5A2 (0.51) | ALDH1A1KDM4EHPGDLMNANOTUM | |
| SCHEMBL3607213 | 0.81 | CCNC (0.53) | ALDH1A1KDM4EGAACYP1A2GLA | |
| SCHEMBL1005097 | 0.78 | CYP1A2 (0.49) | KDM4EL3MBTL1XDHLMNASRD5A1 | |
| SCHEMBL1005747 | 0.78 | MIF (0.45) | ALDH1A1L3MBTL1XDHLMNAGAA | |
| SCHEMBL1005746 | 0.78 | MIF (0.45) | ALDH1A1L3MBTL1XDHLMNAGAA | |
| SCHEMBL31062548 | 0.77 | MAPT (0.37) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL24746391 | 0.73 | HPGD (0.45) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL24744751 | 0.73 | CCNC (0.44) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL24746390 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL21356990 | 0.72 | KDM4E (0.50) | ALDH1A1KDM4EHPGDLMNANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347595-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | Council of Scientific & Industrial Research (IN) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | disclosed |