Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744339 | 0.91 | EGFR (0.47) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL24744763 | 0.91 | NPC1 (0.51) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL24744753 | 0.91 | SLC6A3 (0.46) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL24744391 | 0.91 | SLC6A4 (0.46) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL24744328 | 0.90 | ALDH1A1 (0.41) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL24744327 | 0.88 | ALDH1A1 (0.42) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL24744383 | 0.88 | KDM4E (0.42) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL30115542 | 0.88 | MAPKAPK2 (0.41) | CCNCCDK8ALDH1A1KDM4EHPGD | |
| SCHEMBL24744338 | 0.87 | HPGD (0.41) | CCNCCDK8LMNAALDH1A1KDM4E | |
| SCHEMBL24744345 | 0.87 | ALDH1A1 (0.41) | LMNAALDH1A1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347595-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | Council of Scientific & Industrial Research (IN) | 2024-04-10 | — | — | EP | claimed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | claimed |
| EP-4347595-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | Council of Scientific & Industrial Research (IN) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | disclosed |