Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002248 | 0.91 | HDAC3 (0.48) | PARP1PARP3HDAC3HDAC1HDAC2 | |
| SCHEMBL19520081 | 0.89 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6477908 | 0.88 | DNM1 (0.53) | TDP1DNM1CNR1CERT1PLA2G2C | |
| SCHEMBL7622211 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 | |
| SCHEMBL7624358 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 | |
| SCHEMBL10684284 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 | |
| SCHEMBL7622216 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 | |
| SCHEMBL3100590 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 | |
| SCHEMBL13225189 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 | |
| SCHEMBL7625929 | 0.84 | DNM1 (0.64) | DNM1CNR1CERT1PLA2G2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022260491-A1 | NOVEL INDOLE DERIVATIVE, AND USE THEREOF FOR TREATING DISEASES RELATED TO ADVANCED GLYCATION END PRODUCTS | 주식회사 메타센테라퓨틱스 | 2022-12-15 | — | — | WO | disclosed |