Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 8/20 | 0.50 |
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.46 |
| ▸ | STAT3 | P40763 | 3/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24745279 | 0.91 | PDE6D (0.52) | PDE6DEGFRERBB2STAT3MCL1 | |
| SCHEMBL24744701 | 0.89 | PDE6D (0.50) | PDE6DEGFRERBB2STAT3 | |
| SCHEMBL24744625 | 0.84 | MCL1 (0.49) | PDE6DMCL1 | |
| SCHEMBL24745172 | 0.82 | PDE6D (0.46) | PDE6DSTAT3MCL1 | |
| SCHEMBL24745677 | 0.82 | PDE6D (0.45) | PDE6DEGFRERBB2STAT3 | |
| SCHEMBL24746663 | 0.81 | MCL1 (0.52) | BCL2MCL1 | |
| SCHEMBL24744633 | 0.81 | MCL1 (0.50) | PDE6DEGFRERBB2BCL2MCL1 | |
| SCHEMBL24745295 | 0.80 | MCL1 (0.51) | MCL1 | |
| SCHEMBL30000763 | 0.80 | MCL1 (0.51) | MCL1 | |
| SCHEMBL24745286 | 0.80 | MCL1 (0.51) | PDE6DEGFRERBB2BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |