Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262052 | 0.93 | NR1H2 (0.39) | NR1H2GPR119 | |
| SCHEMBL213460 | 0.86 | EPHX2 (0.44) | GPR119EPHX2HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL20423977 | 0.85 | EPHX2 (0.43) | GPR119EPHX2HRH2HRH1 | |
| SCHEMBL24744833 | 0.84 | GPR119 (0.39) | NR1H2GPR119EPHX2 | |
| SCHEMBL24744870 | 0.83 | NR1H2 (0.46) | NR1H2EPHX2 | |
| SCHEMBL24746774 | 0.82 | NR1H2 (0.39) | NR1H2EPHX2HRH2HRH1 | |
| SCHEMBL29262060 | 0.82 | GPR119 (0.43) | GPR119 | |
| SCHEMBL29262172 | 0.80 | GPR119 (0.40) | GPR119 | |
| SCHEMBL27178679 | 0.80 | NR1H2 (0.48) | NR1H2 | |
| SCHEMBL24742731 | 0.79 | NR1H2 (0.42) | NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |