Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CPS1 | P31327 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630172 | 1.00 | MEN1 (0.64) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL24747199 | 0.85 | SMN1; SMN2 (0.51) | MEN1KMT2AHPGDTSHRGAA | |
| SCHEMBL24745778 | 0.83 | MEN1 (0.64) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL24163473 | 0.81 | MEN1 (0.73) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL24745777 | 0.80 | MEN1 (0.63) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL30630165 | 0.80 | HPGD (0.56) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL24747198 | 0.80 | HPGD (0.56) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL19667102 | 0.77 | LCK (0.65) | HPGDLMNATSHRALDH1A1NPSR1 | |
| SCHEMBL2105339 | 0.77 | HPGD (0.74) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL3308874 | 0.76 | LCK (0.49) | HPGDLMNATSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |