Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24745857 | 0.90 | BACE1 (0.43) | BACE1EGLN2CXCR2CA1CA2 | |
| SCHEMBL24745878 | 0.88 | CNR1 (0.42) | BACE1EGLN2CXCR2CA1CA2 | |
| SCHEMBL24746068 | 0.82 | CXCR2 (0.39) | CXCR2CA1CA2CA9CNR1 | |
| SCHEMBL5918956 | 0.82 | HDAC1 (0.41) | BACE1CXCR2CA1CA2CA9 | |
| SCHEMBL3726907 | 0.82 | CXCR2 (0.41) | CXCR2CA1CA2CA9PDGFRB | |
| SCHEMBL24746078 | 0.81 | CXCR2 (0.36) | BACE1CXCR2CA1CA2CA9 | |
| SCHEMBL25274581 | 0.81 | MET (0.47) | CXCR2KDR | |
| SCHEMBL24746065 | 0.80 | CETP (0.39) | CXCR2CA1CA2CA9CNR1 | |
| SCHEMBL20972012 | 0.80 | IDO1 (0.50) | CXCR2 | |
| SCHEMBL12290584 | 0.80 | ALDH1A1 (0.40) | CXCR2CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |