Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468641 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2ARMAOBTLR4TLR2 | |
| SCHEMBL320455 | 0.83 | MAOB (0.57) | SMN1; SMN2MAOBMAOAPARP15PARP10 | |
| SCHEMBL29597315 | 0.83 | MAOB (0.57) | SMN1; SMN2MAOBMAOAPARP15PARP10 | |
| SCHEMBL19000545 | 0.81 | MAOB (0.58) | SMN1; SMN2MAOBMAOAPARP10MAPK1 | |
| SCHEMBL171645 | 0.81 | MRGPRX4 (0.53) | SMN1; SMN2ARMAOBTLR4TLR2 | |
| SCHEMBL12260777 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2ARMAOBTLR4TLR2 | |
| SCHEMBL17129526 | 0.78 | AR (0.47) | ARMAOBMAOA | |
| SCHEMBL17128894 | 0.77 | RXRA (0.50) | ARMAOBMAOAKMT2A | |
| SCHEMBL8135327 | 0.77 | MAOB (0.54) | SMN1; SMN2MAOBMAOA | |
| SCHEMBL257670 | 0.77 | MAOB (0.45) | SMN1; SMN2ARMAOBMAOANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431365-A | Phenyl heterocyclic derivative-containing regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |