Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479412 | 0.88 | GRM5 (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL2475592 | 0.87 | CHRM4 (0.48) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL16564260 | 0.85 | HDAC2 (0.42) | HDAC2HDAC8HDAC6PDK1NAMPT | |
| SCHEMBL2480143 | 0.81 | EPHX2 (0.43) | EPHX2NAMPTALDH1A1 | |
| SCHEMBL2477516 | 0.81 | ALOX5 (0.46) | ALDH1A1 | |
| SCHEMBL2473352 | 0.79 | NPSR1 (0.58) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2474397 | 0.78 | KMT2A (0.51) | EPHX2LMNAMEN1KMT2A | |
| SCHEMBL13873641 | 0.78 | EPHX2 (0.51) | EPHX1EPHX2NAMPTLMNAC3AR1 | |
| SCHEMBL16564496 | 0.77 | EPHX1 (0.46) | EPHX1NAMPTHSD17B1LMNAKMT2A | |
| SCHEMBL13873672 | 0.77 | EPHX2 (0.52) | EPHX1EPHX2NAMPTLMNAC3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | claimed |
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | disclosed |