Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564546 | 0.85 | RAB9A (0.42) | RAB9ANPC1HSD11B1OPRM1OPRD1 | |
| SCHEMBL2475592 | 0.84 | CHRM4 (0.48) | ALDH1A1 | |
| SCHEMBL2479412 | 0.82 | GRM5 (0.45) | OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL2474641 | 0.81 | EPHX1 (0.45) | EPHX2NAMPTALDH1A1 | |
| SCHEMBL2475564 | 0.80 | FNTA (0.46) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2477516 | 0.80 | ALOX5 (0.46) | ALDH1A1 | |
| SCHEMBL2474397 | 0.79 | KMT2A (0.51) | EPHX2 | |
| SCHEMBL2473352 | 0.77 | NPSR1 (0.58) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2471885 | 0.77 | EPHX2 (0.49) | EPHX2 | |
| SCHEMBL2476302 | 0.77 | EPHX2 (0.43) | EPHX2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | claimed |
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | disclosed |