SCHEMBL28485

SCHEMBL28485

CC(C)Oc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
PARP10 Q53GL7 1/20 0.54
ALDH1A3 P47895 1/20 0.52
ESR2 Q92731 3/20 0.50
MEN1 O00255 2/20 0.50
ESR1 P03372 2/20 0.50
POLB P06746 1/20 0.50
GLA P06280 1/20 0.48
MITF O75030 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LTA4H P09960 2/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1619622 0.93 KMT2A (0.64) KMT2APARP10ALDH1A3ESR2MEN1
SCHEMBL863444 0.93 ESR2 (0.58) KMT2APARP10ALDH1A3ESR2MEN1
SCHEMBL12019129 0.89 ESR1 (0.67) KMT2APARP10ALDH1A3ESR2MEN1
SCHEMBL8002323 0.89 KMT2A (0.47) KMT2APARP10ALDH1A3ESR2MEN1
SCHEMBL5197463 0.87 ESR1 (0.56) KMT2APARP10ALDH1A3ESR2MEN1
SCHEMBL19847794 0.87 NR1H2 (0.56) KMT2APARP10ALDH1A3ESR2MEN1
Hydrogen Peroxide SCHEMBL28902806 0.86 KMT2A (0.70) KMT2APARP10ALDH1A3MEN1POLB
SCHEMBL125543 0.86 ALDH1A3 (0.64) KMT2APARP10ALDH1A3MEN1POLB
Sulfur Dioxide SCHEMBL23421268 0.85 ESR2 (0.50) KMT2APARP10ALDH1A3ESR2MEN1
SCHEMBL12541779 0.85 ESR1 (0.53) KMT2APARP10ALDH1A3ESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114467160-B Solid electrolytic capacitor comprising polyaniline 京瓷AVX元器件公司 2025-04-01 CN claimed
CN-118878815-B High-contrast polyether-ether-ketone material meeting aviation standard requirements and preparation method thereof 江苏君华特种高分子材料股份有限公司 2025-02-11 CN claimed
CN-118878815-A High-contrast polyether-ether-ketone material meeting aviation standard requirements and preparation method thereof 江苏君华特种高分子材料股份有限公司 2024-11-01 CN claimed
EP-3606898-B1 COMPOSITIONS COMPRISING HYDROQUINONE AND CATECHOL, METHOD FOR PREPARING THESE COMPOSITIONS SPECIALTY OPERATIONS FRANCE (FR) 2024-10-02 EP claimed
CN-114945632-B Polyaniline composition, coating film, polyaniline-containing porous body, and method for producing coating film or polyaniline-containing porous body 出光兴产株式会社 2024-07-12 CN claimed
CN-118280737-A Solid electrolytic capacitor comprising polyaniline 京瓷AVX元器件公司 2024-07-02 CN claimed
US-11791106-B2 Solid electrolytic capacitor containing polyaniline KYOCERA AVX Components Corporation (US) 2023-10-17 US claimed
US-11776760-B2 Solid electrolytic capacitor containing polyaniline KYOCERA AVX Components Corporation (US) 2023-10-03 US claimed
CN-114467160-A Solid electrolytic capacitor containing polyaniline 京瓷AVX元器件公司 2022-05-10 CN claimed
US-20220108846-A1 Solid Electrolytic Capacitor Containing Polyaniline KYOCERA AVX Components Corporation 2022-04-07 US claimed
EP-1230219-A1 AROMATIC SULFONS HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. Searle & Co. (US) 2002-08-14 EP claimed
US-20010039287-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR PHARMACIA CORPORATION 2001-11-08 US claimed
US-20010014688-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR BARTA THOMAS E (US) 2001-08-16 US claimed
CN-1279669-A Aromatic sulfone hydroxamic acid metalloprotease inhibitors SEARLE & CO (US) 2001-01-10 CN claimed
EP-1042290-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. SEARLE & CO. (US) 2000-10-11 EP claimed
WO-2000050396-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. SEARLE & CO. (US) 2000-08-31 WO claimed
WO-1999025687-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. SEARLE & CO. (US) 1999-05-27 WO claimed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US claimed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US claimed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010039287-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR MMP13, MMP9, MMP10 KMT2A 1023/4885PARP10 1557/4885ALDH1A3 1505/4885
US-20010014688-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR MMP13, MMP9, MMP10 KMT2A 1023/4885PARP10 1557/4885ALDH1A3 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.