Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626865 | 0.86 | SCN10A (0.36) | HDAC3HDAC1HDAC2HDAC6SCN10A | |
| SCHEMBL10227953 | 0.81 | SCN10A (0.38) | SCN10AGRM1ALDH1A1ESR1CYP2C9 | |
| SCHEMBL1626451 | 0.81 | AR (0.41) | SCN10AGAAMEN1ALDH1A1MAPT | |
| SCHEMBL31347512 | 0.81 | SCN10A (0.37) | SCN10AGAAMEN1ALDH1A1MAPT | |
| SCHEMBL22726812 | 0.81 | SCN10A (0.37) | SCN10AGAAMEN1ALDH1A1MAPT | |
| SCHEMBL604751 | 0.81 | SCN10A (0.34) | SCN10AALDH1A1CYP2C9JAK2ROCK2 | |
| SCHEMBL3533730 | 0.78 | CASP1 (0.42) | SCN10ALMNABRAFCTSA | |
| SCHEMBL12866834 | 0.78 | SCN10A (0.36) | SCN10AGRM1ESR1CYP2C9BRAF | |
| SCHEMBL17157434 | 0.77 | SCN10A (0.34) | SCN10AALDH1A1JAK2ROCK2PRKCQ | |
| SCHEMBL4573201 | 0.77 | AR (0.38) | SCN10AHTR2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |