SCHEMBL24747280

SCHEMBL24747280

Oc1ccc2ccc3c(c2c1)C(c1ccc(-c2ccc(C4c5c(ccc6ccc(O)cc56)Oc5ccc6ccc(O)cc6c54)cc2)cc1)c1c(ccc2ccc(O)cc12)O3

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 1/20 0.47
FGB P02675 1/20 0.47
HPGD P15428 1/20 0.47
TNNI3 P19429 1/20 0.47
TNNT2 P45379 1/20 0.47
RECQL P46063 1/20 0.47
TNNC1 P63316 1/20 0.47
LMNA P02545 1/20 0.46
NPSR1 Q6W5P4 3/20 0.39
ESR1 P03372 7/20 0.38
ESR2 Q92731 7/20 0.38
CFTR P13569 1/20 0.37
GOPC Q9HD26 1/20 0.37
APP P05067 3/20 0.36
SHBG P04278 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15998808 0.94 ESR1 (0.45) MEN1KMT2AALDH1A1FGBHPGD
SCHEMBL15998797 0.89 ESR1 (0.41) MEN1KMT2AALDH1A1FGBHPGD
SCHEMBL22167536 0.88 MEN1 (0.46) MEN1KMT2AALDH1A1FGBHPGD
SCHEMBL19842300 0.88 MEN1 (0.46) MEN1KMT2AALDH1A1FGBHPGD
SCHEMBL17207357 0.88 LMNA (0.51) MEN1KMT2AALDH1A1FGBHPGD
SCHEMBL19806877 0.86 MEN1 (0.49) MEN1KMT2ANPSR1CFTRGOPC
SCHEMBL21971619 0.85 MEN1 (0.56) MEN1KMT2AALDH1A1LMNANPSR1
SCHEMBL21189668 0.84 MEN1 (0.43) MEN1KMT2AALDH1A1FGBHPGD
SCHEMBL15998760 0.84 ESR1 (0.47) MEN1KMT2ANPSR1ESR1ESR2
SCHEMBL15998767 0.84 MEN1 (0.43) MEN1KMT2AALDH1A1FGBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022233919-A2 SPIN ON METAL-ORGANIC FORMULATIONS MERCK PATENT GMBH (DE) 2022-11-10 WO disclosed