SCHEMBL24747894

SCHEMBL24747894

CC1(C)c2ccccc2-c2ccc(N(c3ccc4oc5ccccc5c4c3)c3cc(-c4ccc5ccccc5c4)ccc3-c3ccccc3)cc21

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.31
CASP3 P42574 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30
ALK Q9UM73 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24748354 0.96 PGR (0.32) PGRCASP3SENP7SENP6HSP90AA1
SCHEMBL24751042 0.94 HCRTR1 (0.32) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL17733273 0.93 ALK (0.32) PGRHSP90AA1HSP90AB1CHRNA1CHRNG
SCHEMBL24748951 0.93 HCRTR1 (0.33) PGR
SCHEMBL17853233 0.93 PGR (0.33) PGRHSP90AA1HSP90AB1CHRNA1CHRNG
SCHEMBL20441985 0.91 PGR (0.33) PGR
SCHEMBL24748399 0.91 CHRNA1 (0.31) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL24748742 0.91 CHRNA1 (0.33) HSP90AA1HSP90AB1CHRNA1CHRNGCHRNB1
SCHEMBL27274463 0.90 PGR (0.34) PGRCASP3SENP7SENP6HSP90AA1
SCHEMBL23225304 0.90 CASP3 (0.33) PGRCASP3SENP7SENP6HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022259886-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed