SCHEMBL24748418

SCHEMBL24748418

CC1(C)c2ccccc2-c2cccc(-c3ccc(N(c4ccc(-c5ccc6c(c5)oc5ccccc56)cc4)c4cc(-c5ccc6ccccc6c5)ccc4-c4ccccc4)cc3)c21

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.32
MMP12 P39900 1/20 0.30
MMP13 P45452 1/20 0.30
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24748874 0.95 PLA2G2A (0.31) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL24749644 0.93 CA12 (0.32) HCRTR1MMP12MMP13CHRNA1CHRNG
SCHEMBL24964049 0.93 HCRTR1 (0.32) HCRTR1CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL23233602 0.93 HCRTR1 (0.33) HCRTR1
SCHEMBL23233603 0.93 HCRTR1 (0.33) HCRTR1
SCHEMBL24748951 0.93 HCRTR1 (0.33) HCRTR1MMP12MMP13
SCHEMBL23180847 0.92 HCRTR1 (0.35) HCRTR1MMP12MMP13CHRNA1CHRNG
SCHEMBL23180120 0.92 HCRTR1 (0.35) HCRTR1MMP12MMP13CHRNA1CHRNG
SCHEMBL24749050 0.91 CASP3 (0.32)
SCHEMBL24964047 0.90 HCRTR1 (0.34) HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022259886-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed