SCHEMBL24749467

SCHEMBL24749467

c1ccc(-c2ccc(-c3cc4ccccc4c4ccccc34)cc2N(c2ccc(-c3ccc4sc5ccccc5c4c3)cc2)c2cccc3c2sc2ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
LIMK1 P53667 1/20 0.32
PIM3 Q86V86 2/20 0.31
PIM1 P11309 1/20 0.31
PIM2 Q9P1W9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24749335 0.95 ALOX5 (0.39) ALOX5
SCHEMBL24749332 0.95 ALOX5 (0.39) ALOX5
SCHEMBL24750063 0.94 ALOX5 (0.35) ALOX5
SCHEMBL24750033 0.94 ALOX5 (0.37) ALOX5
SCHEMBL24748536 0.94 ALOX5 (0.39) ALOX5
SCHEMBL24749835 0.93 ALOX5 (0.36) ALOX5
SCHEMBL24749828 0.92 ALOX5 (0.35) ALOX5
SCHEMBL24747829 0.92 PIM3 (0.33) ALOX5PIM3
SCHEMBL24748392 0.92 ALOX5 (0.39) ALOX5
SCHEMBL24749131 0.91 PIM3 (0.35) ALOX5LIMK1PIM3PIM1PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022259886-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed