Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639392 | 1.00 | CHRM2 (0.44) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| SCHEMBL4250620 | 0.94 | CHRM2 (0.50) | CHRM2ALDH1A1L3MBTL1MEN1GAA | |
| SCHEMBL18878630 | 0.82 | CHRM2 (0.45) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| SCHEMBL500406 | 0.82 | ALDH1A1 (0.48) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| SCHEMBL25202526 | 0.82 | ALDH1A1 (0.48) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL1376064 | 0.80 | ALDH1A1 (0.47) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| SCHEMBL4177818 | 0.79 | ALDH1A1 (0.50) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| SCHEMBL23959763 | 0.78 | TSHR (0.37) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ETACR1 | |
| SCHEMBL18878755 | 0.77 | ALDH1A1 (0.51) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 | |
| SCHEMBL27887097 | 0.77 | HRH3 (0.41) | CHRM2ALDH1A1HRH3L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |