Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24307669 | 0.94 | TSHR (0.39) | TSHRPOLBPKMKDM4EAPEX1 | |
| SCHEMBL29952365 | 0.81 | ACE (0.40) | POLBTACR1L3MBTL1OGFRL1 | |
| SCHEMBL29952267 | 0.81 | ACE (0.40) | POLBTACR1L3MBTL1OGFRL1 | |
| SCHEMBL28570207 | 0.80 | L3MBTL1 (0.47) | POLBKDM4ETACR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6962733 | 0.79 | ALDH1A1 (0.37) | POLBKDM4EL3MBTL1DPP4PREP | |
| SCHEMBL2639392 | 0.78 | CHRM2 (0.44) | TSHRPOLBKDM4ETACR1L3MBTL1 | |
| SCHEMBL24749679 | 0.78 | CHRM2 (0.44) | TSHRPOLBKDM4ETACR1L3MBTL1 | |
| SCHEMBL4957090 | 0.76 | TSHR (0.35) | TSHRPOLBPKMKDM4EAPEX1 | |
| SCHEMBL8935820 | 0.76 | CYP2C19 (0.42) | KDM4ESMN1; SMN2 | |
| SCHEMBL7764760 | 0.76 | POLB (0.50) | TSHRPOLBPKML3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214278-A2 | REGIOSELECTIVE OXIDATION OF HETEROCYCLIC ALPHA-AMINO AMIDES | PHARMAZELL GMBH (DE) | 2021-10-28 | — | — | WO | disclosed |