SCHEMBL2474976

SCHEMBL2474976

Brc1ccc2cc(-c3ccc4oc5ccccc5c4c3)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP2A6 P11509 1/20 0.46
TNKS O95271 1/20 0.45
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
MAOB P27338 1/20 0.42
AHR P35869 2/20 0.42
IDO1 P14902 1/20 0.42
GABRP O00591 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802294 0.90 MAPT (0.52) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL2472033 0.89 CYP2A6 (0.52) SMN1; SMN2CYP2A6TNKSCASP3SENP7
SCHEMBL19152584 0.88 CYP2A6 (0.47) SMN1; SMN2CYP2A6TNKSCASP3SENP7
SCHEMBL1637337 0.87 MAPT (0.49) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL18086159 0.86 MAPT (0.52) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL29601539 0.86 TNKS (0.54) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL21428322 0.86 TNKS (0.54) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL30775072 0.86 TNKS (0.54) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL3043527 0.86 TNKS (0.54) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL74802 0.86 TNKS (0.54) NPC1MAPTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2713415-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2018-12-19 EP disclosed
US-9461251-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-10-04 US disclosed
US-9461251-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-10-04 US disclosed
US-9461251-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-10-04 US disclosed
EP-2163550-B1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2015-09-09 EP disclosed
US-8940412-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-8940412-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-8940412-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-20130313538-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SONY CORPORATION (JP) 2013-11-28 US disclosed
US-8512875-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-08-20 US disclosed
US-8512875-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-08-20 US disclosed
US-20110315965-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-12-29 US disclosed
US-20110315965-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-12-29 US disclosed
US-20110315965-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-12-29 US disclosed
CN-102265424-A Material for organic electroluminescent element and organic electroluminescent element 2011-11-30 CN disclosed
EP-2372803-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2011-10-05 EP disclosed
EP-2163550-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-03-17 EP disclosed
US-20080315754-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-12-25 US disclosed
US-20080315754-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-12-25 US disclosed
US-20080315754-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080315754-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME APRT, ETFA, MLLT3 NPC1 4617/4885MAPT 1133/4885KDM4E 1540/4885
US-20110315965-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, TERF2, BPTF NPC1 2789/4885MAPT 196/4885KDM4E 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.