SCHEMBL24749799

SCHEMBL24749799

c1ccc(C2(c3ccccc3)c3ccccc3-c3c(N(c4cc(-c5ccc6ccccc6c5)ccc4-c4ccc5ccccc5c4)c4cccc5ccccc45)cccc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24749246 0.97 CHRNA1 (0.32) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL23457962 0.95 GPR84 (0.33) GPR84HDAC4HDAC2HDAC8SLC6A2
SCHEMBL23458420 0.93 CA12 (0.31) GPR84CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL26001528 0.93 CA12 (0.31) GPR84CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL23458421 0.92 ESR1 (0.32) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL24747816 0.92 HDAC4 (0.33) HDAC4HDAC2HDAC8CHRNA1CHRNG
SCHEMBL24772227 0.92 CA12 (0.34)
SCHEMBL24747765 0.90 HSD17B1 (0.33) HDAC4HDAC2HDAC8CHRNA1CHRNG
SCHEMBL24747810 0.90 MCL1 (0.31) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL24747815 0.89 HDAC4 (0.33) HDAC4HDAC2HDAC8SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022259886-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed