Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDC7 | O00311 | 3/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801555 | 0.94 | PTGS2 (0.49) | PTGS2CNR1EGFRCDK2CDC7 | |
| SCHEMBL21801500 | 0.89 | CDC7 (0.50) | PTGS2CNR1EGFRCDK2CDC7 | |
| SCHEMBL21801557 | 0.83 | CNR1 (0.52) | PTGS2CNR1EGFRCDK2 | |
| SCHEMBL21801479 | 0.81 | QPCT (0.48) | PTGS2CNR1EGFRTP53GAA | |
| SCHEMBL21801499 | 0.81 | BCL2 (0.50) | TP53MGAMGAASIMGAM2 | |
| SCHEMBL21801498 | 0.80 | GSK3B (0.46) | PTGS2CNR1EGFRTP53GAA | |
| SCHEMBL21801526 | 0.77 | CDC7 (0.48) | CNR1CDK2CDC7CCNE1DBF4 | |
| SCHEMBL21801525 | 0.76 | MAPT (0.53) | EGFRTP53POLBSMN1; SMN2NPC1 | |
| SCHEMBL21801490 | 0.73 | QPCT (0.44) | CNR1NPC1RAB9ALMNAMAPT | |
| SCHEMBL21801474 | 0.73 | NPC1 (0.46) | EGFRCDK2CDC7CCNE1DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220257569-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257569-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | CNR2, GPR119, CNR1 | PTGS2 1785/4885PIK3CD 711/4885PIK3R1 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.