Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645919 | 0.84 | CTSK (0.40) | CTSKGPR88CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25697742 | 0.83 | HDAC6 (0.36) | CTSKALDH1A1CA14CA1CA7 | |
| SCHEMBL20715722 | 0.83 | HDAC6 (0.36) | CTSKALDH1A1CA14CA1CA7 | |
| SCHEMBL17144567 | 0.83 | HDAC6 (0.36) | CTSKALDH1A1CA14CA1CA7 | |
| SCHEMBL16941095 | 0.82 | CTSK (0.39) | CTSKALDH1A1GPR88CHRNB2CHRNB4 | |
| SCHEMBL3711368 | 0.81 | CTSK (0.38) | CTSKGPR88CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25918858 | 0.81 | CTSK (0.37) | CTSKGPR88CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19695796 | 0.80 | CTSK (0.38) | CTSKGPR88CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24764190 | 0.80 | CTSK (0.36) | CTSKGPR88CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2917271 | 0.79 | HDAC6 (0.39) | CTSKGPR88CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-11661431-B2 | Thienopyrrole compounds | GILEAD SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | CTSK 2023/4885ALDH1A1 2343/4885GPR88 3163/4885 |
| US-11661431-B2 | Thienopyrrole compounds | SSB, TPMT, LCP2 | CTSK 2023/4885ALDH1A1 2343/4885GPR88 3163/4885 |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | CTSK 2023/4885ALDH1A1 2343/4885GPR88 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.