Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25134723 | 1.00 | CTSS (0.40) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL24113318 | 1.00 | CTSS (0.40) | CTSSCTSKIDO1ITGAVITGB6 | |
| SCHEMBL24113103 | 0.93 | CTSL (0.42) | — | |
| SCHEMBL25835207 | 0.93 | CTSL (0.42) | — | |
| SCHEMBL24020461 | 0.93 | CTSL (0.42) | — | |
| SCHEMBL24013950 | 0.93 | CTSL (0.42) | — | |
| SCHEMBL23824309 | 0.92 | CTSS (0.48) | CTSSCTSK | |
| SCHEMBL24020645 | 0.92 | — | — | |
| SCHEMBL23824306 | 0.92 | CTSS (0.48) | CTSSCTSK | |
| SCHEMBL29063369 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266363-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022265577-A2 | CORONAVIRUS ENZYME MODULATORS, METHODS OF SYNTHESIS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-12-22 | — | — | WO | disclosed |