Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 19/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443443 | 1.00 | GHSR (0.53) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL2436649 | 0.88 | GHSR (0.57) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL15603793 | 0.86 | GHSR (0.52) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL12328232 | 0.85 | GHSR (0.52) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL2441635 | 0.85 | GHSR (0.66) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL12299437 | 0.82 | GHSR (0.55) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL12329331 | 0.81 | GHSR (0.54) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL2438302 | 0.81 | GHSR (0.76) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL2438384 | 0.80 | GHSR (0.46) | GHSRCHRM2CYP3A4HTR2BKCNH2 | |
| SCHEMBL2438383 | 0.80 | GHSR (0.46) | GHSRCHRM2CYP3A4HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609680-B2 | 2,3-dihydro-1H-inden-1-yl-2,7-diazaspiro[3.5] nonane derivatives | PFIZER INC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-20110230461-A1 | 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES | PFIZER INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230461-A1 | 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES | GIPR, GLP1R, GHSR | GHSR 3/4885CHRM2 826/4885CYP3A4 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.