Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 5/20 | 0.37 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16897943 | 1.00 | CAPN1 (0.41) | CAPN1PSMB2PSMB1PSMB5SLC7A5 | |
| SCHEMBL13039705 | 1.00 | CAPN1 (0.41) | CAPN1PSMB2PSMB1PSMB5SLC7A5 | |
| SCHEMBL2475740 | 0.92 | CAPN1 (0.46) | CAPN1SLC7A5CTSBLARS1 | |
| SCHEMBL9572309 | 0.92 | CAPN1 (0.46) | CAPN1SLC7A5CTSBLARS1 | |
| SCHEMBL8817388 | 0.92 | CAPN1 (0.46) | CAPN1SLC7A5CTSBLARS1 | |
| SCHEMBL3487246 | 0.92 | CAPN1 (0.46) | CAPN1SLC7A5CTSBLARS1 | |
| SCHEMBL16565969 | 0.92 | CAPN1 (0.46) | CAPN1SLC7A5CTSBLARS1 | |
| SCHEMBL4226580 | 0.88 | CTSK (0.43) | PSMB2PSMB1PSMB5SLC7A5CTSB | |
| SCHEMBL4226584 | 0.88 | CTSK (0.43) | PSMB2PSMB1PSMB5SLC7A5CTSB | |
| SCHEMBL16566020 | 0.86 | DPP8 (0.42) | CAPN1PSMB2PSMB1PSMB5CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015104292-A2 | COMPOUNDS FOR USE IN TREATING OR PREVENTING CANCEROUS DISEASES | BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS (GR) | 2015-07-16 | — | — | WO | claimed |
| WO-2024192252-A2 | USE OF SMALL MOLECULES TO INCREASE HYPOXIA INDUCIBLE FACTOR (HIF) ACTIVITY | BROWN UNIVERSITY (US) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024118561-A2 | DYSREGULATION OF NEUROPROTEASOMES BY APOE ISOFORMS DRIVES ENDOGENOUS TAU AGGREGATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-06-06 | — | — | WO | disclosed |
| US-20130142784-A1 | METHOD OF TREATING TUMOR RESISTANT TO HERCEPTIN OR PACLITAXEL USING FOXM1 INHIBITORS AND DETECTING SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2009152462-A2 | METHOD OF REGULATING CELL GROWTH USING A PROTEASOME INHIBITOR | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-12-17 | — | — | WO | disclosed |