Sugi Predict

Sugi Predict / Compounds / SCHEMBL247591

SCHEMBL247591

SCHEMBL247591

O=C(OC(=O)c1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 2/20 0.65
▸ CES1 P23141 2/20 0.65
▸ TSHR P16473 2/20 0.54
▸ LMNA P02545 2/20 0.54
▸ ALOX15 P16050 1/20 0.54
▸ F2 P00734 1/20 0.54
▸ MAPT P10636 3/20 0.50
▸ L3MBTL1 Q9Y468 3/20 0.50
▸ NR4A1 P22736 1/20 0.50
▸ KMT2A Q03164 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ HPGD P15428 1/20 0.49
▸ NPC1 O15118 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ SRD5A2 P31213 1/20 0.48
▸ NR1I2 O75469 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ AHR P35869 1/20 0.47
▸ TAAR1 Q96RJ0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL3127994 0.92 CES2 (0.55) CES2CES1TSHRALOX15MAPT
SCHEMBL28775846 0.91 CES2 (0.59) CES2CES1TSHRLMNAALOX15
SCHEMBL247590 0.91 CES2 (0.59) CES2CES1TSHRLMNAALOX15
Nitrous Acid SCHEMBL28218509 0.91 CES2 (0.55) CES2CES1TSHRLMNAALOX15
SCHEMBL28073554 0.90 CYP1A2 (0.58) CES2CES1TSHRALOX15MAPT
SCHEMBL19875730 0.90 CES2 (0.59) CES2CES1TSHRLMNAALOX15
SCHEMBL19875729 0.90 CES2 (0.59) CES2CES1TSHRLMNAALOX15
SCHEMBL18050327 0.90 CES2 (0.59) CES2CES1TSHRLMNAALOX15
SCHEMBL18050328 0.90 CES2 (0.59) CES2CES1TSHRLMNAALOX15
SCHEMBL27584084 0.89 CES2 (0.53) CES2CES1ALOX15L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119752442-A Method for preparing different fluorescence emission carbon points in large scale through solvent engineering 中南大学 2025-04-04 — — CN claimed
CN-114031639-B Preparation method of biphospide with P-O-C-P structure 烟台大学 2024-07-12 — — CN claimed
CN-117417363-A Preparation method for synthesizing organic borate compound from anhydride compound 北京理工大学 2024-01-19 — — CN claimed
CN-115433149-B Preparation method of 3,3', 4' -biphenyl tetracarboxylic dianhydride 天津众泰材料科技有限公司 2023-12-26 — — CN claimed
CN-117105826-A HNO-releasable compound and preparation method thereof 海南大学 2023-11-24 — — CN claimed
CN-116514750-A Production process of 2, 3',4' -biphenyl tetracarboxylic dianhydride 安徽秀朗新材料科技有限公司 2023-08-01 — — CN claimed
CN-115894380-A N-aryl substituted imino ester compound and preparation method and application thereof 上海特化医药科技有限公司 2023-04-04 — — CN claimed
US-20220289684-A1 BENZIMIDAZOLE SUBSTITUTION-BASED PHENYL N-BUTYRAMIDE COMPOUND AND PREPARATION METHOD THEREFOR SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2022-09-15 — — US claimed
CN-114031639-A Preparation method of biphosphonate with P-O-C-P structure 烟台大学 2022-02-11 — — CN claimed
CN-112708114-B Low-dielectric high-light-transmittance polyarylate, polyarylate film and preparation method thereof 四川大学 2021-11-23 — — CN claimed
CN-1526710-A Prepn of 4-chlorophthalic anhydride 华东师范大学 2004-09-08 — — CN claimed
CN-1485304-A One-step production of high-purity trimellitic acid from pseudocumene 宁波市贝特化工新材料有限公司 2004-03-31 — — CN claimed
CN-1109013-C Separation of isomers of chloro-benzoic anhydride CHANGCHUN APPLIED CHEMISTRY (CN) 2003-05-21 — — CN claimed
CN-1090171-C Process for preparation of monochlorobenzoyl oxide by liquid phase air oxidation HEILONGJING PROV PETROLEUM CHE (CN) 2002-09-04 — — CN claimed
CN-1367192-A Preparation method of dichlorophthalein imide and dichlorodiphenylketone or dichlorodiphenylsulfone copolymer CHANGCHUN APPLIED CHEMISTRY (CN) 2002-09-04 — — CN claimed
CN-1295999-A Process for preparation of monochlorobenzoyl oxide by liquid phase air oxidation HEILONGJIANG PROVINCIAL PETROL (CN) 2001-05-23 — — CN claimed
EP-0638545-B1 Process for preparing 1,2-diacyl-2-t-alkylhydrazides ROHM & HAAS (US) 1999-10-13 — — EP claimed
CN-1186063-A Separation of isomers of chloro-benzoic anhydride SHENYANG APPLIED CHEMISTRY INS (CN) 1998-07-01 — — CN claimed
EP-0638545-A1 Process for preparing 1,2-diacyl-2-t-alkylhydrazides ROHM AND HAAS COMPANY (US) 1995-02-15 — — EP claimed
EP-0002151-B1 PROCESS FOR THE SYNTHESIS OF ESTERS OF PARACHLOROBENZOYL-PHENOXY-ISOBUTYRIC ACID LABORATOIRES FOURNIER S.A. (FR) 1983-05-25 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289684-A1 BENZIMIDAZOLE SUBSTITUTION-BASED PHENYL N-BUTYRAMIDE COMPOUND AND PREPARATION METHOD THEREFOR PAH, PNP, CYP3A4 CES2 3047/4885CES1 2989/4885TSHR 4202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.