Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050328 | 1.00 | CES2 (0.59) | CES2CES1TSHRLMNAALOX15 | |
| SCHEMBL19875730 | 1.00 | CES2 (0.59) | CES2CES1TSHRLMNAALOX15 | |
| SCHEMBL18050327 | 1.00 | CES2 (0.59) | CES2CES1TSHRLMNAALOX15 | |
| SCHEMBL18050295 | 0.92 | CES2 (0.52) | CES2CES1TSHRLMNAALOX15 | |
| SCHEMBL18050293 | 0.92 | CES2 (0.52) | CES2CES1TSHRLMNAALOX15 | |
| SCHEMBL247591 | 0.90 | CES2 (0.65) | CES2CES1TSHRLMNAALOX15 | |
| SCHEMBL18050253 | 0.88 | LMNA (0.61) | CES2CES1TSHRLMNAF2 | |
| SCHEMBL18050252 | 0.88 | LMNA (0.61) | CES2CES1TSHRLMNAF2 | |
| SCHEMBL18069318 | 0.88 | LMNA (0.61) | CES2CES1TSHRLMNAF2 | |
| SCHEMBL19875818 | 0.83 | CES2 (0.60) | CES2CES1TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246532-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-04-02 | — | — | US | disclosed |
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | C1S, CCNT1, COG1 | CES2 3660/4885CES1 2579/4885TSHR 2458/4885 |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | C1S, CCNT1, COG1 | CES2 3660/4885CES1 2579/4885TSHR 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.