Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25881766 | 0.87 | OPRL1 (0.42) | OPRL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25764635 | 0.87 | OPRL1 (0.42) | OPRL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27268254 | 0.86 | OPRL1 (0.43) | OPRL1OPRK1HDAC3HDAC4HDAC1 | |
| SCHEMBL25748810 | 0.85 | OPRL1 (0.41) | OPRL1OPRK1HDAC3HDAC4HDAC1 | |
| SCHEMBL25649781 | 0.84 | OPRL1 (0.41) | OPRL1OPRK1HDAC3HDAC4HDAC1 | |
| SCHEMBL25875278 | 0.83 | OPRK1 (0.43) | OPRL1OPRK1 | |
| SCHEMBL24342135 | 0.83 | OPRL1 (0.37) | OPRL1OPRK1ALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL22757206 | 0.82 | OPRL1 (0.39) | OPRL1OPRK1ALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL24342162 | 0.82 | OPRL1 (0.39) | OPRL1OPRK1ALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL24342120 | 0.82 | OPRL1 (0.39) | OPRL1OPRK1ALDH1A1SMN1; SMN2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262789-A1 | ANTITUMOR COMPOUND AND USE THEREOF | 明慧医药（杭州）有限公司 | 2022-12-22 | — | — | WO | disclosed |