Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25881766 | 1.00 | OPRL1 (0.42) | OPRL1ALDH1A1SMN1; SMN2FOLH1FAAH | |
| SCHEMBL27268254 | 0.94 | OPRL1 (0.43) | OPRL1ALDH1A1SMN1; SMN2FOLH1OPRD1 | |
| SCHEMBL25748810 | 0.93 | OPRL1 (0.41) | OPRL1ALDH1A1SMN1; SMN2FOLH1OPRD1 | |
| SCHEMBL23515709 | 0.90 | FOLH1 (0.43) | OPRL1ALDH1A1SMN1; SMN2FOLH1FAAH | |
| SCHEMBL25649781 | 0.89 | OPRL1 (0.41) | OPRL1ALDH1A1SMN1; SMN2FOLH1OPRD1 | |
| SCHEMBL23680214 | 0.87 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2FOLH1HDAC3HDAC4 | |
| SCHEMBL24760256 | 0.87 | OPRL1 (0.39) | OPRL1ALDH1A1SMN1; SMN2OPRD1PSMB5 | |
| SCHEMBL22757206 | 0.87 | OPRL1 (0.39) | OPRL1ALDH1A1SMN1; SMN2OPRD1ACE | |
| SCHEMBL24342162 | 0.86 | OPRL1 (0.39) | OPRL1ALDH1A1SMN1; SMN2OPRD1ACE | |
| SCHEMBL26595672 | 0.86 | OPRL1 (0.41) | OPRL1ALDH1A1SMN1; SMN2OPRD1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685742-B2 | Anti-tumor compound and preparation method and use thereof | DUALITY BIOLOGICS (SUZHOU) CO., LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685742-B2 | Anti-tumor compound and preparation method and use thereof | RCC2, REN, VHL | OPRL1 3888/4885ALDH1A1 3602/4885SMN1; SMN2 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.