Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.57 |
| ▸ | SLC9A2 | Q9UBY0 | 3/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 11/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312663 | 0.88 | SLC9A1 (0.71) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| SCHEMBL6314722 | 0.84 | SLC9A1 (0.51) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| SCHEMBL30142173 | 0.84 | SLC9A1 (0.51) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| Hydrochloric Acid SCHEMBL6321779 | 0.84 | SLC9A1 (0.79) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| Hydrochloric Acid SCHEMBL6321772 | 0.83 | SLC9A1 (0.57) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| SCHEMBL6312241 | 0.81 | SLC9A1 (0.45) | SLC9A1SLC9A2SPRMALT1 | |
| SCHEMBL6312945 | 0.80 | NFE2L2 (0.57) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| SCHEMBL6262880 | 0.79 | SLC9A1 (0.74) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| Hydrochloric Acid SCHEMBL7686352 | 0.78 | SLC9A1 (0.74) | SLC9A1SLC9A2NFE2L2KEAP1OPRM1 | |
| SCHEMBL24760447 | 0.77 | MALT1 (0.66) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120427-A | MALT1 inhibitor and preparation method and application thereof | 上海拓界生物医药科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022262855-A1 | MALT1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海拓界生物医药科技有限公司 | 2022-12-22 | — | — | WO | disclosed |
| WO-2022262855-A1 | MALT1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海拓界生物医药科技有限公司 | 2022-12-22 | — | — | WO | disclosed |