Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124739 | 0.85 | KMT2A (0.37) | HTTKMT2AMAPT | |
| SCHEMBL12514790 | 0.77 | KMT2A (0.46) | HTTKMT2AGBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL9114926 | 0.77 | AGBL2 (0.41) | HTTSMN1; SMN2MAPT | |
| SCHEMBL15080876 | 0.75 | S1PR1 (0.37) | HTTKMT2AGBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL15699752 | 0.75 | SMN1; SMN2 (0.36) | HTTKMT2AGBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL15773977 | 0.74 | KMT2A (0.43) | HTTKMT2ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL2069010 | 0.73 | HTT (0.43) | HTTKMT2AGBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL18179659 | 0.73 | PLAU (0.42) | HTTKMT2AGBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL16693756 | 0.73 | HTT (0.34) | HTTKMT2AGBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL23383733 | 0.73 | SMN1; SMN2 (0.37) | HTTKMT2AGBA1SMN1; SMN2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199677-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-09-29 | — | — | WO | disclosed |