Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | IL6ST | P40189 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14141084 | 0.76 | CHRM2 (0.40) | MAPT | |
| SCHEMBL6964149 | 0.71 | KMT2A (0.36) | MAPTKMT2A | |
| SCHEMBL248703 | 0.71 | MME (0.43) | MAPTPOLBITGB1ITGA5ITGA4 | |
| SCHEMBL6978352 | 0.70 | KMT2A (0.39) | POLBITGB1ITGA5ITGA4ITGB3 | |
| SCHEMBL34474446 | 0.69 | MAPT (0.35) | MAPTPOLBACE | |
| SCHEMBL10160264 | 0.69 | — | — | |
| SCHEMBL15817780 | 0.68 | DPP4 (0.42) | MAPTPOLBPIK3CD | |
| SCHEMBL22978565 | 0.67 | AR (0.34) | MAPTPOLBITGB1ITGA5ITGA4 | |
| SCHEMBL3607555 | 0.67 | AR (0.34) | MAPTPOLBITGB1ITGA5ITGA4 | |
| SCHEMBL3336957 | 0.67 | AR (0.34) | MAPTPOLBITGB1ITGA5ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000608-A2 | NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES | GLUESENKAMP KARL-HEINZ (DE) | 2012-01-05 | — | — | WO | disclosed |