Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581498 | 0.86 | MME (0.39) | MMEPOLBMAPTNR3C2ACE | |
| SCHEMBL7561265 | 0.76 | ITGB1 (0.41) | MMEPOLBITGB1ITGA5ITGA4 | |
| SCHEMBL6967927 | 0.74 | ITGB1 (0.37) | POLBITGB1ITGA5MAPTITGA4 | |
| SCHEMBL10903692 | 0.72 | SMN1; SMN2 (0.39) | MMEPOLBMAPTNR3C2ACE | |
| SCHEMBL10903685 | 0.72 | SMN1; SMN2 (0.39) | MMEPOLBMAPTNR3C2ACE | |
| SCHEMBL247623 | 0.71 | MAPT (0.40) | MMEPOLBITGB1ITGA5MAPT | |
| SCHEMBL6686977 | 0.68 | POLB (0.36) | POLBITGB1ITGA5MAPTITGA4 | |
| SCHEMBL6972069 | 0.68 | HRH3 (0.39) | KMT2A | |
| SCHEMBL6972067 | 0.68 | HRH3 (0.39) | KMT2A | |
| SCHEMBL18716370 | 0.67 | MME (0.33) | MMEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000608-A2 | NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES | GLUESENKAMP KARL-HEINZ (DE) | 2012-01-05 | — | — | WO | disclosed |