Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960969 | 0.67 | CREBBP (0.37) | — | |
| SCHEMBL6968269 | 0.67 | CREBBP (0.37) | — | |
| SCHEMBL27046282 | 0.66 | CACNA2D1 (0.45) | KMT2AITGB1ITGA4ITGA5ITGB3 | |
| SCHEMBL6964149 | 0.63 | KMT2A (0.36) | KMT2A | |
| SCHEMBL8112083 | 0.60 | KMT2A (0.48) | KMT2A | |
| SCHEMBL1853020 | 0.60 | GAA (0.47) | KMT2ARIPK1 | |
| SCHEMBL74366 | 0.58 | SRC (0.56) | — | |
| SCHEMBL1171114 | 0.57 | GABBR2 (0.53) | — | |
| Acetic Acid SCHEMBL3416047 | 0.56 | CYP2D6 (0.48) | KMT2A | |
| Hydrochloric Acid SCHEMBL8340022 | 0.56 | SRC (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |