⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23806005 | 0.82 | CYP2D6 (0.32) | — | |
| SCHEMBL21106891 | 0.82 | CYP2D6 (0.32) | — | |
| SCHEMBL24673411 | 0.78 | GBA1 (0.32) | — | |
| SCHEMBL21106883 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL21106632 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL25006291 | 0.72 | — | — | |
| SCHEMBL23945120 | 0.72 | — | — | |
| SCHEMBL11048329 | 0.72 | INMT (0.34) | — | |
| SCHEMBL11048326 | 0.72 | INMT (0.34) | — | |
| SCHEMBL21105704 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-11-10 | — | — | US | disclosed |