Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308679 | 0.90 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL514780 | 0.89 | TGFBR1 (0.38) | TGFBR1 | |
| SCHEMBL10751312 | 0.81 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL10748960 | 0.81 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL10751321 | 0.79 | TGFBR1 (0.37) | TGFBR1 | |
| SCHEMBL1517401 | 0.79 | TGFBR1 (0.37) | TGFBR1 | |
| SCHEMBL10753309 | 0.79 | TGFBR1 (0.37) | TGFBR1 | |
| SCHEMBL15309161 | 0.78 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL307976 | 0.78 | TSHR (0.41) | — | |
| SCHEMBL9396211 | 0.78 | TGFBR1 (0.39) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374031-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010071691-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2010-06-24 | — | — | WO | disclosed |