Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308679 | 0.98 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL10748960 | 0.89 | TGFBR1 (0.33) | TGFBR1 | |
| Acrylamide SCHEMBL2476539 | 0.89 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL10751312 | 0.89 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL515436 | 0.88 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL10751321 | 0.86 | TGFBR1 (0.37) | TGFBR1 | |
| SCHEMBL1517401 | 0.86 | TGFBR1 (0.37) | TGFBR1 | |
| SCHEMBL15309161 | 0.86 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL9396211 | 0.85 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL10753636 | 0.83 | TGFBR1 (0.35) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20250387989-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2025-12-25 | — | — | US | claimed |
| EP-4657145-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| EP-4657144-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| US-20220281190-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC. (CH) | 2022-09-08 | — | — | US | claimed |
| US-11364695-B2 | Silicone hydrogel lenses with water-rich surfaces | ALCON INC. (CH) | 2022-06-21 | — | — | US | claimed |
| US-20200339836-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC. (CH) | 2020-10-29 | — | — | US | claimed |
| US-10781340-B2 | Silicone hydrogel lenses with water-rich surfaces | ALCON INC. (CH) | 2020-09-22 | — | — | US | claimed |
| US-20190055427-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC. (CH) | 2019-02-21 | — | — | US | claimed |
| US-20180044549-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC. (CH) | 2018-02-15 | — | — | US | claimed |
| EP-2513711-B1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2017-07-12 | — | — | EP | claimed |
| US-9322960-B2 | Method of making a contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2016-04-26 | — | — | US | claimed |
| US-20150247956-A1 | METHOD OF MAKING A CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2015-09-03 | — | — | US | claimed |
| US-9005492-B2 | Methods for making silicone hydrogel lenses from water-based lens formulations | NOVARTIS AG (CH) | 2015-04-14 | — | — | US | claimed |
| US-8883051-B2 | Methods for increasing the ion permeability of contact lenses | NOVARTIS AG (CH) | 2014-11-11 | — | — | US | claimed |
| US-20110140292-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | ALCON INC. (CH) | 2011-06-16 | — | — | US | claimed |
| US-20110133350-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | ALCON INC. (CH) | 2011-06-09 | — | — | US | claimed |
| US-7939579-B1 | Hydrogels and methods of manufacture | CONTAMAC LIMITED (GB) | 2011-05-10 | — | — | US | claimed |
| US-4711943-A | IMPROVED OXYGEN PERMEABILITY AND STABILITY | SOLA U.S.A. INC. (US) | 1987-12-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | CRYZ, STRA6, PHOSPHO1 | TGFBR1 302/4885 |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | STRA6, CRYZ, SMCHD1 | TGFBR1 252/4885 |
| US-20250387989-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | PHOSPHO1, MYOC, ASS1 | TGFBR1 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.