Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 9/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24764839 | 0.90 | FOLH1 (0.46) | FOLH1CPB2SLC6A5SLC15A2GNPAT | |
| SCHEMBL7446481 | 0.88 | FOLH1 (0.53) | FOLH1CPB2SLC6A5GSRRNPEP | |
| SCHEMBL8985000 | 0.88 | FOLH1 (0.53) | FOLH1CPB2SLC6A5GSRRNPEP | |
| SCHEMBL22315428 | 0.88 | FOLH1 (0.53) | FOLH1CPB2SLC6A5GSRRNPEP | |
| SCHEMBL25767678 | 0.86 | NMT1 (0.40) | FOLH1CPB2SIRT6SIRT1NMT2 | |
| SCHEMBL28416333 | 0.84 | FOLH1 (0.49) | FOLH1CPB2SLC6A5GSRRNPEP | |
| SCHEMBL15905676 | 0.84 | SIRT6 (0.42) | FOLH1CPB2SIRT6SIRT1NMT2 | |
| SCHEMBL23758316 | 0.84 | SIRT6 (0.42) | FOLH1CPB2SIRT6SIRT1NMT2 | |
| SCHEMBL29558361 | 0.83 | FOLH1 (0.57) | FOLH1CPB2SLC6A5SLC15A2GNPAT | |
| SCHEMBL23053207 | 0.83 | NMT1 (0.43) | FOLH1CPB2SIRT6SIRT1NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | FOLH1 21/4885CPB2 54/4885SLC6A5 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.